If there is no cell depend on other cells, then you can copy everything and paste it to another text editor, like Notepad or Notepad++
After you paste them to your text editor (I'll explain only notepad and notepad++), you will see that each cells are separated by a single tab.
if you're using notepad, copy each one of those tabs, press Ctrl + H (find and replace), paste the tab on the "Find", and paste a comma [ , ] on the replace with.
then, replace all.
If you're using notepad++, press Ctrl + H (Find and replace), type [ \t ] on the Find, and type a comma [ , ] on the "replace with". then, select search mode: extended.
don't just copy paste the thing I write. the things you put there shall have no white space, except the tab you copied.
make sure you copy everything properly. at last, do some cleaning up if needed.
number 2 is possible. just modify the values.